Direct TV’s Technology Complements Its Programming

While it’s well known that Direct TV provides a wide variety of high quality programming on hundreds of television and satellite radio channels, not many people know about the impressive space age satellite technology that goes into delivering that programming to over fifteen and a half million subscribers.

While there are some types of technology that are available on special order, Direct TV also provides some pretty impressive technology to all of its subscribers regardless of which programming package they sign up for. The most basic technology is digital television. Television programming in digital format provides a vividly crystal clear picture in all but the worst weather conditions. That’s because digital television is easily cleansed of any interference that it picks up during transmission by Direct TV’s sophisticated satellite receiver equipment.

Direct TV also provides great user friendly software to all of its subscribers. User friendly software like the on screen program guide and Parental Locks make it much easier to handle the hundreds of channels that you could have available to you if you sign up for one of the larger programming packages. The on screen program guide is probably the piece of software that you’ll use the most. It displays a listing of all of the television shows and movies that you can choose among right on your TV screen. Along with each program, the on screen program guide will also provide you with information about the program- like who stars in it and what the plot consists of- in order to help you decide whether or not it’s something you might want to watch. While the on screen program guide is on the screen, the picture from the channel that the system is tuned to will continue to be displayed in a small window in the corner of the screen and the audio will continue to play over the speakers. That way you won’t have to miss anything while you’re looking around.

Direct TV’s Parental Controls help you to manage all of the channels, by providing you with tools to prevent your children from watching inappropriate programming. You can enact blanket rules, like blocking access to all movies with certain MPAA ratings, or you can block out specific programs and channels. Parental Controls are extremely flexible tools that can provide you with all the peace of mind you need to leave your kids alone with the TV.

One of the optional technologies you can get from Direct TV is a Digital Video Recorder. Digital Video Recorders are built into some satellite receivers and provide a great way to record the TV shows and movies that you want to watch, but wouldn’t otherwise be able to see because of other obligations like work, family, and community. This practice of recording programming so that it can be watched later is called “time shifting” and a Digital Video Recorder is extremely useful for “time shifting” because it’s easy to program, can store a huge amount of video on its hard disk, and even record video from two separate channels at the same time! As an added bonus, all of the video that it records is stored and played back with the same high quality picture and sound of Direct TV’s original broadcast.

Another optional technology supplied by Direct TV is HDTV. HDTV is a next generation television format that features a high resolution picture and wide screen along with a sophisticated sound format. All of these differences mean that you need a special TV set, a special receiver, and special programming to watch HDTV. Direct TV can provide everything that you need to enjoy this technology right now, except for the HDTV set.

Direct TV provides a lot of great technology that will enhance your television experience.

Preformulation and Formulation Development

Optimizing Conformational Stability and Biological ActivityMaintenance of the native three dimensional conformation is critical for the long term stability and biological activity of biotherapeutics. Biophysical characterization techniques such as circular dichroism, differential scanning calorimetry, FTIR, dynamic light scattering, and fluorescence spectroscopy provide a mechanism to assess the conformational and thermodynamic stability of proteins under a range of formulation conditions. These tools allow development scientists to differentiate various various buffer, pH, ionic strength, and excipient conditions, and identify the conditions that confer the optimum environment for the therapeutic protein.

Utilizing Advanced Statistical Design for Preformulation Development Preformulation development includes statistical design of experiments, allowing simultaneous evaluation of multiple factors and evaluation of interactions between factors. It is crucial to use advanced biophysical characterization techniques to evaluate the conformational stability of large molecules in addition to traditional methods for evaluation of chemical stability.

A large molecule preformulation development program typically includes the following activities:
Evaluate the effect of pH, buffer type, and ionic strength on solubility.
Evaluate the effect of various excipients on improving solubility if necessary.
Evaluate effects of pH, buffer type, and excipients on conformational stability.
Evaluate the effect of pH, buffers, excipients and ionic strength on physical and chemical stability.
Utilize a statistical design approach to identify the optimal conditions for structural, physical and chemical stability.
Perform forced degradation to elucidate product degradation pathways and to demonstrate the stability-indicating capacity of the analytical methods.
Forced degradation studies typically include restricted oxidation, deamidation, aggregation (via agitation), and / or acid / base hydrolysis.
Evaluation of heat stress, photo stress, and freeze thaw are also performed.

Looking for information on Analytical Development and other related resources?

Formulation Development for Numerous Dosage FormsFormulation development includes dosage forms for parenteral, oral topical and inhalation administration, including liquids, gels, suspensions, emulsions and lyophilized powders. Formulation scientists are highly skilled in the development of the dosage forms most relevant to biotherapeutics, with particular expertise in lyophilization and development of stable liquid formulations for proteins. High concentration antibody formulation development for subcutaneous administration requires particular emphasis on viscosity and tonicity. Lyophilization cycle development is performed in the context of the unique thermodynamic properties of the API to deliver an efficient, scalable, transferable process resulting in optimum product stability and reconfiguration characteristics. Formulation development capabilities also include:

Effect of excipients on solubility, tonicity, and viscosity Evaluation of antioxidant and conservative compatibility Container-closure compatibility Long term and accelerated stability studies.

Advantages of Formulation Development Approach. This outlined approach to preformulation and formulation development result in significant savings to the client by eliminating the variables associated with suboptimal formulations. Preclinical development efforts in PK, PD, ADME and toxicology occur with confidence that additional uncontrollable variables from unstable formulations are not introduced into the study. This benefit extends far into clinical trials as well, where assessment of toxicity, dosage levels and efficiency are substantially influenced by an optimal formulation that preserves the three dimensional conformation of the therapeutic protein. By eliminating uncontrolled stability variables, the focus is placed solely on the therapeutic performance and clinical outcome.

Make Money With Niche Marketing

You can have a good income with niche marketing, but you will have to do a certain amount of work each month to keep the site up to date.

It is interesting that many people try to start their online business by selling products on how to make money online when they are not successful themselves. But there is a lot of money to make online when you start to work in non Internet Marketing niches.

The best way to earn a good income is to have either a website or a blog which you host on your own website. That way you can have total control on what you include.

Once you have decided on your niche, you need to either write your own content or have some written for you. Then you need to have some products to promote.

Now you might think this is harder to do than it actually is. Stop, and think for a moment, if you are careful about your weight, how many diet books you have bought. You may have bought many that you have never read. But anyone with a weight problem will buy every diet book in the hope to find that secret diet tip that will get them slim overnight or in a short time without any work.

When a person is passionate about a subject, they will be ready to buy anything that will further their knowledge in that niche. Time and time again, people are doing this offline, and they will not change their habits because it is now online.

It may take time for them to build up confidence in you and your site, but with good quality information they will soon be aware of how trustworthy you are.

Within your niche you will learn other areas that people want, and will be able to promote those items as well. As you develop your niche site, you will be able to move into more and more products, and you will find that you are able to earn more and more money online.

Once you have a good plan, start created as many niche sites as you can, while maintaining a high quality standard. It's OK to start off small. If you can create one 5-page niche site a week, you will be doing very well.

There is money to be made through niche marketing but like any business online you will need to do some work.

Technology in Education

Technology has moved at a fast pace over the last decade. Wouldn’t you agree? As a result, many technologies have replaced the need for human resources in some fields, and it has also impacted education drastically.

Before delving into the impacts of technology on education however, consider:

· How travel agents have been largely replaced by online reservation systems.

· In 1901, Charles Holland Duel stated that “Everything that can be invented has been invented”. This was over one century ago, where numerous inventions had yet to be patented and trademarked.

· The number one focus on this list of technological impacts, is how computers and the internet has affected lifestyles and education. Everything can be shared in an instant, and snail mail is no longer the main method of communication. In the past one had to wait a few days before receiving a message, unless a phone or fax were used.

In the 21st century, educational institutions have moved with the times by integrating technology into learning. After all, our educational systems are a critical part of societal norms.

Here are some of the key ways that technology has broadened teaching horizons:

Traditional colleges have adopted online methods of learning, which is otherwise known as online colleges. No longer do students have to relocate from thousands of miles away to get a quality education. All that’s needed is a computer and connection to the internet to plug into online learning.

This has opened up numerous doors for working adults who have previously been restricted by time and resources. The technology of online videos or recorded tutorials allows students to study on their own time, whether day or night.

A study by US News purports that nearly 6.1 million students were enrolled in online college course in 2011. This number is expected to grow as the stigma of online certification has somewhat been lifted due to its increasing popularity in the workplace.

Other ways that technology affects education include the student’s ability to research faster than ever, compared to pouring over books in the library. As an example, a study by the Pew Research Center suggests that digital technologies have helped students to become more self-sufficient researchers.

Educators too have integrated technology into learning, with the distribution of course material and online video, voice, or written tutorials for student references.

Finally, there has also been a dynamic shift in the communication between students and teachers via online, social and digital mediums.